The five-year survival rate has been reported to be between 57 and 85%. Lobectomy with hilar and mediastinal lymphadenectomy is the standard surgical treatment for stage I NSCLC. Surgical resection remains the cornerstone of therapy for stage I NSCLC. As low-dose CT screening has become more widespread, more early-stage lung cancers have been screened. Lung cancer has been divided into two main histological types: small cell lung cancer (SCLC) accounts for 15–25% of all lung cancer cases, and non-small cell lung cancer (NSCLC) accounts for approximately the remaining 75–85%. Worldwide, lung cancer has the highest incidence and mortality of all cancers, with 2.1 million new lung cancer cases and 1.8 million deaths in 2018. The minimal ablative margin is an independent factor of NSCLC relapse after MWA, and the fusion of 3D reconstruction technique can feasibly assess the minimal ablative margin. The feasibility of 3D quantitative analysis of the ablative margins after MWA for NSCLC has been validated. The 1-year and 2-year distant metastasis-free rates were 94.4% and 86.6%, respectively the 1-year and 2-year disease-free survival rates were 88.9% and 63.7%, respectively. In the group with a minimal ablative margin ≥ 5 mm, the 1-year and 2-year local progression-free rates were 88.9% and 69.4%, respectively. The 1-year and 2-year distant metastasis-free rates were 75.6% and 75.6%, respectively the 1-year and 2-year disease-free survival rates were 16.7% and 11.1%, respectively. In the group with a minimal ablative margin < 5 mm, the 1-year and 2-year local progression-free rates were 35.7% and 15.9%, respectively. Univariate and multivariate analyses indicated that tumor size (hazard ratio = 1.91, P < 0.01 HR = 2.41, P = 0.01) and minimal ablative margin (HR = 0.13, P < 0.01 HR = 0.11, P < 0.01) were independent prognostic factors for the LTP interval. The minimal ablative margin was measured using the fusion of 3D computed tomography reconstruction technique. We retrospectively analyzed 36 patients with stage I NSCLC lesions undergoing MWA and analyzed the relationship between minimal ablative margin and the local tumor progression (LTP) interval, the distant metastasis interval and disease-free survival (DFS). To assess the ablative margin of microwave ablation (MWA) for stage I non-small cell lung cancer (NSCLC) using a three-dimensional (3D) reconstruction technique.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |